Guideline No. 315: Prevention of Ovarian Hyperstimulation Syndrome
نویسندگان
چکیده
Summary Statements1.The particular follicle-stimulating hormone formulation used for ovarian stimulation does not affect the incidence of hyperstimulation syndrome. (I)2.Coasting may reduce severe (III)3.Coasting longer than 3 days reduces in vitro fertilization pregnancy rates. (II-2)4.The use either luteinizing or human chorionic gonadotropin final oocyte maturation influence (I)5.There is no clear published evidence that lowering dose will result a decrease rate (III)6.Cabergoline starting from day syndrome patients at higher risk and appear to lower (II-2)7.Avoiding by freezing all embryos prevent prolonged high risk. (II-2)8.Pregnancy rates are affected when using gonadotropin-releasing (GnRH) agonists GnRH antagonist protocols egg frozen vitrification later transfer. (II-2)Recommendations1.The addition metformin should be considered with polycystic who undergoing because it (I-A)2.Gonadotropin dosing carefully individualized, taking into account patient’s age, body mass, antral follicle count, previous response gonadotropins. (II-3B)3.Cycle cancellation before administration gonadatropin an effective strategy prevention syndrome, but emotional financial burden imposes on cycle cancelled. (III-C)4.Gonadotropin-releasing recommended (OHSS). The OHSS have very robust can reduced agonist as substitute trigger maturation. (I-B)5.A protocol donor fertility preservation cycles. (III-C)6.Albumin other plasma expanders time retrieval (I-E)7.Elective single embryo transfer (III-C)8.Progesterone, rather gonadotropin, luteal phase support. (I-A)9.Outpatient culdocentesis disease progression (II-2B)
منابع مشابه
Prevention of Ovarian Hyperstimulation Syndrome
Ovarian hyperstimulation syndrome (OHSS) is rare but most serious complication of ovarian stimulation. Symptoms are mainly related to increased capillary permeability leading to extravasation of fluid into extravascular compartment. Disease pathophysiology is linked to hCG (human chorionic gonadotropin) which acts through angiogenic molecule vascular endothelial growth factor (VEGF). There is r...
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The following review aims to examine the available evidence to guide best practice in preventing ovarian hyperstimulation syndrome (OHSS). As it stands, there is no single method to completely prevent OHSS. There seems to be a benefit, however, in categorizing women based on their risk of OHSS and individualizing treatments to curtail their chances of developing the syndrome. At present, both A...
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The ovarian hyperstimulation syndrome (OHSS) is a potentially fatal condition with a pathophysiology that is not clearly understood. A shift in fluid from the extravascular space occurs, thought to be induced by cytokines and/or vascular endothelial growth factor. Human chorionic gonadotrophin (hCG), exogenous or endogenous, seems to be the triggering mechanism, resulting in early and late deve...
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The Ovarian Hyperstimulation Syndrome (OHSS) represents one of the biggest nightmares of all physicians involved in Assisted Reproductive Technologies (ART). Every year, several hundreds of women are hospitalized and to date several deaths have been reported. The pivotal event in the development of OHSS is the disruption of capillary integrity that results in leakage of intravascular fluid and ...
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ژورنال
عنوان ژورنال: Journal of obstetrics and gynaecology Canada
سال: 2023
ISSN: ['1701-2163', '2665-9867']
DOI: https://doi.org/10.1016/j.jogc.2023.05.005